Cel-Shading in the video game industry has only appeared in a few non-animation based games, such as Jet Grind Radio, Rez, and The Legend of Zelda: Wind Waker. There are two advantages to Cel-Shading:
1. Better FPS. A lot of the time there's a lack of complex texture. Though the lighting is very stressed, the GPU doesn't have to process a lot of high VRAM using textures.
2. More of a animated look. For cases when you want a cartoon looking scene rather than a realistic one, and when flat shading just doesn't look right.